Hi brownbear324,
If you have any antivirus or firewall programs installed on your computer, please temporarily disable them and then attempt to scan again. If you still experience difficulty, we can see if there are some files in a folder called TWAIN_32 other than those related to the scanner that may be causing a conflict with the scanning process. If there are, temporarily moving these files may resolve the issue.
To move the non-Canon Twain files from the Twain_32 folder, please follow these steps:
1. Right-click the Start button, click on Run, then type in twain_32.
2. Inside of the TWAIN_32 folder, you should see a folder for your printer as well as a WIATWAIN.DS file. If there are other files in that folder, you will want to move them to another location (preferably your Desktop) by doing the following:
2-1. Click on each of the other items in the folder other than the WIATWAIN.DS file and folder related to your printer to select them. You will then want to hold the the CTRL key on your keyboard while selecting each of the items until all of the items except for the two referenced above are selected. Please be sure to leave the WIATWAIN.DS file and folder related to your printer inside of the TWAIN_32 folder.
2-2. With all of the items you want to move selected, please go to the EDIT menu and select the CUT option. You can also press the CTRL+X keys on your keyboard to perform the Cut function.
2-3. Go to your Desktop and right-click your mouse in any blank area, then choose the PASTE option. The items you selected from the TWAIN_32 folder should appear on the Desktop.
Once the items have been moved, please attempt to scan again. If you still experience difficulty, we ask that you please call 1-866-261-9362, Monday - Friday 10:00 a.m. - 10:00 p.m. ET (excluding holidays) for further assistance. A Canon technical support representative will be happy to help. There is no charge for this call.